Identifying Endometrial Delay Improves Treatment Outcome in Women with Thin Endometrium and Infertility

Authors

  • Narangerel Namshir Department of Obstetrics and Gynecology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia https://orcid.org/0000-0003-1979-6793
  • Yanjinsuren Darmaa Department of Obstetrics and Gynecology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Munkhtsetseg Davaatseren Department of Obstetrics and Gynecology, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Bum Chae Choi Creation and Love Women’s Hospital, Ulaanbaatar, Mongolia

DOI:

https://doi.org/10.24079/cajms.2024.02.003

Keywords:

Endometrium, Delay, Maturation, Receptivity, Reproductive Outcome, Pregnancy

Abstract

Objective: To determine the impact of endometrial delay on reproductive outcomes.

Method: We enrolled 62 infertility women with thin endometrium pre- and post-study in 2020-2023. Infertile women with an endometrial thickness of <7 mm were included and followed in the study. All participants had endometrial delay determined and adjusted be­fore initial Assisted reproductive technologies (ART). After, infertility treatment was started. ART outcomes were evaluated by endometrial thickness and implantation rate. Endometrial thickness was compared to pre-hormone replacement treatment at 48 and 72 hours post-hor­mone therapy. Results: The study included 62 women aged 26-45 who were diagnosed with infertility and thin endometrium. Endometrial thickness was sufficiently increased before and after treatment for all participants. Histological analysis diagnosed endometrial delay (not ap­propriate WOI) in 73.6% of all women. After adjusting the WOI in study participants, there was a statistically significant increase in endometrial thickness post-hormone replacement therapy. The study participants were women who had failed at least one implantation, and the im­plantation rate after WOI adjustment was 58.5%. Conclusions: In 70% of infertility women, endometrial is delayed. In women with thin endometrium, the precise determination of WOI increases ART treatment outcomes.

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Published

2024-06-30

How to Cite

Namshir, N., Darmaa, Y., Davaatseren, M., & Choi, B. C. (2024). Identifying Endometrial Delay Improves Treatment Outcome in Women with Thin Endometrium and Infertility. Central Asian Journal of Medical Sciences, 10(2), 57–66. https://doi.org/10.24079/cajms.2024.02.003

Issue

Vol. 10 No. 2 (2024)

Section

Articles

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